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Image Search Results
Journal: Scientific Reports
Article Title: NLRP3 inflammasome: Pathogenic role and potential therapeutic target for IgA nephropathy
doi: 10.1038/srep41123
Figure Lengend Snippet: Caspase-1 activity (a) and IL-1β secretion (b) measured by ELISA in glomerular primary MCs from untreated wild type or NLRP3 KO mice, which were incubated for 24 h with IgA ICs and 30 min ATP. Caspase-1 activity (c) and IL-1β secretion (d) measured by ELISA in renal TECs, which were incubated for 24 h with IgA ICs and 30 min ATP. The data are expressed as the mean ± SEM for three separate experiments. * p < 0.05. WT, wild type. ns, no significant difference. MCs, mesangial cells. TECs, tubular epithelial cells. IgA ICs, IgA immune complexes.
Article Snippet: Murine J774A.1 macrophages (TIB-67TM), murine
Techniques: Activity Assay, Enzyme-linked Immunosorbent Assay, Incubation